Revakinagene Taroretcel-lwey (Into the eye)

Revakinagene Taroretcel-lwey (rev-a-KIN-a-jeen tar-oh-RET-sel - lwey)

Treats idiopathic macular telangiectasia type 2 (MacTel).

Brand Name(s):

Encelto

When This Medicine Should Not Be Used:

How to Use This Medicine:

Implant

• An eye doctor will give you this medicine in a hospital or clinic. This medicine is an implant that is inserted through the white part of the eye (sclera) by a doctor.
• Your doctor will ask you to avoid heavy lifting and keep water out of your eyes for one week after surgery. You will also need to use eyeglasses or protective eyewear during the day and an eye shield at night for one week after the surgery.
• Your doctor will ask you to use eye drops (including steroid medicine) and topical antibiotic solution starting the day after surgery for 7 days.
• Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

• Some medicines can affect how revakinagene taroretcel-lwey works. Tell your doctor if you are using aspirin, a blood thinner, or NSAIDs.

Warnings While Using This Medicine:

• Tell your doctor if you are pregnant or breastfeeding, or if you have other eye problems or bleeding problems.
• This medicine may cause serious eye or vision problems (including eye infection or bleeding, cataracts, implant extrusion, loss of vision, retinal detachment or tear, or suture-related problems).
• This medicine may cause delayed dark adaptation (ability of the eye to adjust from bright lighting to dark lighting conditions). Drive with caution when moving from bright to dark areas. Use flashlights or night lights at home. Wear sunglasses or tinted lenses in bright areas.
• Do not drive, use machinery, or do anything else that could be dangerous until your eye shield can be removed and you can see.
• Tell your doctor that you have this medicine implanted in your eye before you have an MRI.
• Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Bleeding in your eye
• Blurred vision, seeing floating spots, sensitivity to light
• Eye pain, swelling, redness, or itching of your eyes or eyelids
• Irritated, dry, or watery eyes, a feeling that something is in your eyes

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 5/4/2025